Currently Enrolling
COPD
Phase 2
Study ID: NSI-8226-205

COPD — ZION Study

Sponsored by Uniquity One

Official Study Title
A Phase 2, Randomized, Double-blind, Placebo-controlled, Multiple Dose Ranging Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Solrikitug in Participants with Chronic Obstructive Pulmonary Disease (ZION)
Sponsor
Uniquity One
Phase
Phase 2
Indication
Chronic Obstructive Pulmonary Disease (COPD)
Duration
Contact us for details
About This Study

Objective

To assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of solrikitug 375 mg every 4 weeks (Q4W) on blood eosinophil counts compared with placebo in all participants.

Who Can Participate

Key Eligibility Criteria

Below are the main inclusion and exclusion criteria for this study. The full eligibility assessment will be discussed with you by our research team during screening.

Key Inclusion Criteria

  • Adults 40–75 years
  • Physician-diagnosed COPD
  • Smoking history ≥10 pack-years
  • Stable COPD (no recent acute exacerbation)
  • Post-bronchodilator FEV₁/FVC < 0.70
  • Able to comply with study visits and procedures

Key Exclusion Criteria

  • Current diagnosis of asthma or other significant lung disease
  • Recent COPD exacerbation or respiratory infection
  • Clinically significant uncontrolled comorbidities
  • Use of prohibited medications
  • Pregnant or breastfeeding
Get Started

Apply for this study

Fill out the form below to see if you qualify. Our research coordinators will contact you directly to discuss your eligibility — there's no obligation to participate.

Your information is kept confidential and only used for study eligibility purposes.

Research team discussing clinical study data in laboratory
Why Participate

Advancing research, one participant at a time.

Clinical trials depend on volunteers like you. By participating, you gain access to potential new treatments while helping researchers discover safer, more effective therapies for everyone.

  • Access to investigational treatments and expert medical care
  • Close monitoring by our experienced research team
  • Contribute to better treatments for future patients
  • Confidential — your information is protected at every step