Currently Enrolling
COPD
Phase 2
Study ID: C4531031

Pfizer COPD Umbrella Study

Sponsored by Pfizer

Official Study Title
An Interventional Phase 2, Randomized, Double-Blind, Third Party-Unblinded, Placebo-Controlled, Parallel-Group, Adaptive, Umbrella Study to Investigate Efficacy and Safety of PF-07275315 and PF-07264660 in Adult Participants with Moderate-To-Very Severe Chronic Obstructive Pulmonary Disease
Sponsor
Pfizer
Phase
Phase 2
Indication
Moderate-to-Very Severe COPD
Duration
Contact us for details
About This Study

Concept

This adaptive study evaluates two different investigational drugs (PF-07275315 and PF-07264660) against a common placebo in participants with COPD.

Who Can Participate

Key Eligibility Criteria

Below are the main inclusion and exclusion criteria for this study. The full eligibility assessment will be discussed with you by our research team during screening.

Key Inclusion Criteria

  • Adults with moderate-to-very severe COPD
  • Age 35 to 80 years
  • History of COPD exacerbations
  • Subgroups focused on high blood eosinophil counts (≥300 cells/µL)

Key Exclusion Criteria

  • History of other significant lung diseases (e.g., asthma, pulmonary fibrosis)
  • Recent use of prohibited medications including certain biologics or systemic steroids
Get Started

Apply for this study

Fill out the form below to see if you qualify. Our research coordinators will contact you directly to discuss your eligibility — there's no obligation to participate.

Your information is kept confidential and only used for study eligibility purposes.

Research team discussing clinical study data in laboratory
Why Participate

Advancing research, one participant at a time.

Clinical trials depend on volunteers like you. By participating, you gain access to potential new treatments while helping researchers discover safer, more effective therapies for everyone.

  • Access to investigational treatments and expert medical care
  • Close monitoring by our experienced research team
  • Contribute to better treatments for future patients
  • Confidential — your information is protected at every step